Kleine Moleküle & Peptide

(R,S)-N-Desmethyl PK11195

Precursor for (R,S)-[N-Methyl-¹¹C-]PK11195

1-(2-Chlorophenyl)-N-(1-methylpropyl)-isoquinoline-3-carboxamide-(R,S)

CA index name: 3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N-(1-methylpropyl),-(R,S)

Qualität

Research Chemical

Eigenschaften

Molare Masse 338.83

CAS RN [124236-61-9]

Reinheit ≥ 95 %

  • Colorless crystals

Zertifikate

CoA: appearance, ¹H NMR spectrum

Literatur

Camsonne R. et al. Synthesis of N-[¹¹C]methyl, N-(methyl-1-propyl), (chloro-2-phenyl)-1-isoquinoline carboxamide-3 (PK11195): a new ligand for peripheral benzodiazepine receptors. J. Labelled Compd. Radiopharm. 1984, 21, 985–991.

Hashimoto K. et al. Synthesis and evaluation of ¹¹C-PK11195 for in vivo study of peripheral-type benzodiazepine receptors using positron emission tomography. Ann. Nucl. Med. 1989, 3, 63–71.

Shah F. et al. Synthesis of the Enantiomers of [N-methyl-¹¹C]PK 11195 and Comparison of their Behaviours as Radioligands for PK Binding Sites in Rats. Nucl. Med. Biol. 1994, 21, 573–581.

Cremer J.E. et al. The Distribution of Radioactivity in Brains of Rats Given [N-methyl-¹¹C]PK11195 In Vivo After Induction of a Cortical Ischaemic Lesion. Int. J. Rad. Appl. Instrum. B, 1992, 19, 159–166.

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ProduktnummerFüllmengeAnzahl
Produktnummer: 1640Füllmenge: 1 mg
Produktnummer: 1640Füllmenge: 2 mg
Produktnummer: 1640

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