Kleine Moleküle & Peptide

MMSE (GMP)

Präkursor für 16α-[¹⁸F]Fluoroestradiol

3-(Methoxymethoxy)-1,3,5(10)-gonatriene-16β,17β diol-16,17-cyclic sulfate; 3-O-(Methoxymethyl)-16,17-O-sulfuryl-16-epiestriol; 3-Methoxymethyl-16β,17β-epiestriol-O-cyclic sulfone; FES precursor

CA index name: Estra-1,3,5(10)-triene-16,17-diol, 3-(methoxymethoxy)-, cyclic sulfate, (16β,17β)-

Qualität

GMP Product

Eigenschaften

Molare Masse 394.48

CAS RN [177714-21-5]

Literatur

Roemer J. et al. Automated production of n.c.a. 16α-[¹⁸F]fluoroestradiol. Forschungszent. Rossendorf, [Ber.] FZR 1997, 200, 188–192.

Lim J.L. et al. The use of 3-methoxymethyl-16α,17β-epiestriol-O-cyclic sulfone as the precursor in the synthesis of [¹⁸F]-16α-fluoroestradiol. Nucl. Med. Biol. 1996, 23, 911–915.

Roemer J. et al. ¹³C NMR spectroscopic characterization of estra-1,3,5(10)-triene-3,17β-diol and 3,16,17-triols, and some of their 3-O-methoxymethyl and 16α-fluoro derivatives. Forschungszent. Rossendorf, [Ber.] FZR 1996, 122, 27–30.

Berridge M.S. et al. Cyclic sulfates: useful substrates for selective nucleophilic substitution. J. Org. Chem. 1990, 55, 1211–1217.

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Produktnummer: 1901

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