Kleine Moleküle & Peptide

UCB-J precursor

Precursor for [¹¹C]UCB-J

[¹¹C]UCB-J precursor

(R)-3-(Difluoroboranyl)-4-((2-oxo-4-(3,4,5-trifluorophenyl)pyrrolidin-1-l)methyl)-pyridin-1-ium fluoride

Qualität

Research Chemical

Eigenschaften

Molare Masse 374.09

CAS RN [not yet assigned]

Reinheit ≥ 97 %

  • colorless to off-white solid

Zertifikate

CoA: appearance, ¹H and ¹⁹F NMR spectra, HPLC, chiral HPLC

Literatur

Nabulsi N. et al. Synthesis and Preclinical Evaluation of ¹¹C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain. J. Nucl. Med. 2016, 57, 777–784.

Mercier J. et al. Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein 2A (SV2A) Ligands with Single-Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands. Chem. Med. Chem. 2014, 9, 693–698.

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ProduktnummerFüllmengeAnzahl
Produktnummer: 3420
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