Kleine Moleküle & Peptide
6-O-Desmethyl Donepezil
Precursor for [¹¹C]Donepezil
2-[(1-benzylpiperidin-4-yl)methyl]-6-hydroxy-5-methoxyindan-1-one; 2-((1-benzylpiperidin-4-yl)methyl)-6-hydroxy-5-methoxy-2,3-dihydro-1H-inden-1-one; 1-benzyl-[(6-hydroxy-5-methoxy-1-indanon)-2-yl]methylpiperidine; [¹¹C]Donepezil precursor
2-(1-Benzyl-piperidin-4-ylmethyl)-6-hydroxy-5-methoxy-indan-1-one
Qualität
Research Chemical
Eigenschaften
Molare Masse 365.47
CAS RN [120013-56-1]
Reinheit ≥ 95 %
- Colorless solid
Zertifikate
CoA: appearance, ¹H NMR spectrum
Literatur
De Vos F. et al. Pharmacological evaluation of [¹¹C]donepezil as a tracer for visualization of acetylcholinesterase by PET. Nucl. Med. Biol. 2000, 27, 745–747.
Okamura N. et al. In vivo visualization of donepezil binding in the brain of patients with Alzheimer's disease. Br. J. Clin. Pharmacol. 2008, 65, 472–479.
Gjerløff T. et al. In vivo imaging of human acetylcholinesterase density in peripheral organs using ¹¹C-donepezil: dosimetry, biodistribution, and kinetic analyses. J. Nucl. Med. 2014, 55, 1818–1824.
Gjerløff T. et al. Imaging acetylcholinesterase density in peripheral organs in Parkinson's disease with ¹¹C-donepezil PET. Brain 2015, 138, 653–663.
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| Produkt | Produktnummer | Füllmenge | Anzahl | ||
|---|---|---|---|---|---|
| /de/Produkte/Kleine-Molekuele-und-Peptide/chemical/203ead93-774b-4db2-8761-d66259ea17bf | Precursor | Produktnummer: 2162 | Füllmenge: 1 mg | ||
| /de/Produkte/Kleine-Molekuele-und-Peptide/chemical/203ead93-774b-4db2-8761-d66259ea17bf | Precursor | Produktnummer: 2162 |
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