NITTP (GMP)
Präkursor für [¹⁸F]FMISO ([¹⁸F]Fluormisonidazol)
1-(2'-Nitro-1'-imidazolyl)-2-O-tetrahydropyranyl-3-O-toluenesulfonyl-propanediol; 3-(2-Nitroimidazol-1-yl)-2-O-tetrahydropyranyl-1-O-toluenesulfonylpropanediol
CA index name: 1H-imidazole-1-propanol, 2-nitro-β-[(tetrahydro-2H-pyran-2-yl)oxy]-, 4-methylbenzenesulfonate (ester)
Qualität
GMP Product
Eigenschaften
Molare Masse 425.46
CAS RN [150196-34-2]
Reinheit ≥ 97 %
- Yellowish solid
- primary packaging material: 2 ml dark glass vials (DIN 2R)
- designed for [¹⁸F]FMISO production using the GE FX(F-N) synthesis module
Zertifikate
CoA: appearance, NMR and IR spectra (identity), HPLC (purity), GC (residual solvents), microbiology test
Literatur
Oh S.J. et al. Fully automated synthesis of [¹⁸F]fluoromisonidazole using a conventional [¹⁸F]FDG module. Nucl. Med. Biol. 2005, 32, 899–905.
Lim J.L. et al. An efficient radiosynthesis of [¹⁸F]Fluoromisonidazole. Appl. Radiat. Isot. 1993, 44, 1085–1091.
Martin G.V. et al. Noninvasive detection of hypoxic myocardium using [¹⁸F]Fluoromisonidazole and positron emission tomography. J. Nucl. Med. 1992, 33, 2202–2208.
Rasey J.S. et al. Radiolabeled fluoromisoindazole as an imaging agent for tumor hypoxia. Int. J. Radiat. Oncol. Biol. Phys. 1989, 17, 985–991.
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Produkt | Produktnummer | Füllmenge | Anzahl | ||
---|---|---|---|---|---|
/de/Produkte/Kleine-Molekuele-und-Peptide/chemical/23e59168-4a82-46fd-ac2c-6f68968024c5 | Precursor | Produktnummer: 1401 | Füllmenge: 5 mg | ||
/de/Produkte/Kleine-Molekuele-und-Peptide/chemical/23e59168-4a82-46fd-ac2c-6f68968024c5 | Precursor | Produktnummer: 1401 |