Kleine Moleküle & Peptide

DFO*-Sq

Complexation agent for [⁸⁹Zr]-Labelling, immuno-PET

DFO*-squaramide

N1-(27-((2-ethoxy-3,4-dioxocyclobut-1-en-1-yl)amino)-11,22-dihydroxy-7,10,18,21-tetraoxo-6,11,17,22-tetraazaheptacosyl)-N1-hydroxy-N⁴-(5-(N-hydroxyacetamido)pentyl)succinamide

Qualität

Research Chemical

Eigenschaften

Molare Masse 885.03

CAS RN [not yet assigned]

Reinheit ≥ 90 %

  • Colorless to off-white solid
  • soluble in dimethyl sulfoxide

Zertifikate

CoA: ¹H NMR spectrum (identity), HPLC (purity)

Literatur

Chomet et al. Head-to-head comparison of DFO* and DFO chelators: selection of the best candidate for clinical ⁸⁹Zr-immuno-PET. Eur. J. Nucl. Med. Mol. Imaging 2021, 48, 694–707.

Berg et al. Total-body PET and highly stable chelators together enable meaningful ⁸⁹Zr-antibody PET studies up to 30 days after injection. J. Nucl. Med. 2020, 61, 453–460.

Vizier R. et al. Moving Beyond Isothiocyanates: A Look at the Stability of Conjugation Links Toward Radiolysis in ⁸⁹Zr-Labeled Immunoconjugates. Bioconjugate Chem. 2024, 35, 633–637.

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ProduktnummerFüllmengeAnzahl
Produktnummer: 7274

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