DFO*-Sq
Complexation agent for [⁸⁹Zr]-Labelling, immuno-PET
DFO*-squaramide
N1-(27-((2-ethoxy-3,4-dioxocyclobut-1-en-1-yl)amino)-11,22-dihydroxy-7,10,18,21-tetraoxo-6,11,17,22-tetraazaheptacosyl)-N1-hydroxy-N⁴-(5-(N-hydroxyacetamido)pentyl)succinamide
Qualität
Research Chemical
Eigenschaften
Molare Masse 885.03
CAS RN [not yet assigned]
Reinheit ≥ 90 %
- Colorless to off-white solid
- soluble in dimethyl sulfoxide
Zertifikate
CoA: ¹H NMR spectrum (identity), HPLC (purity)
Literatur
Chomet et al. Head-to-head comparison of DFO* and DFO chelators: selection of the best candidate for clinical ⁸⁹Zr-immuno-PET. Eur. J. Nucl. Med. Mol. Imaging 2021, 48, 694–707.
Berg et al. Total-body PET and highly stable chelators together enable meaningful ⁸⁹Zr-antibody PET studies up to 30 days after injection. J. Nucl. Med. 2020, 61, 453–460.
Vizier R. et al. Moving Beyond Isothiocyanates: A Look at the Stability of Conjugation Links Toward Radiolysis in ⁸⁹Zr-Labeled Immunoconjugates. Bioconjugate Chem. 2024, 35, 633–637.
Zur Anfrage hinzufügen
Produkt | Produktnummer | Füllmenge | Anzahl | ||
---|---|---|---|---|---|
/de/Produkte/Kleine-Molekuele-und-Peptide/chemical/3920891e-e432-4a0c-ac8d-d0b043ca3552 | Chemicals | Produktnummer: 7274 |