Kleine Moleküle & Peptide
ASEM precursor
Precursor for [¹⁸F]ASEM
[¹⁸F]ASEM precursor; [¹⁸F]JHU82132 precursor; 4-(6-Nitro-5,5-dioxo-5H-5l6-dibenzothiophen-3-yl)-1,4-diaza-bicyclo[3.2.2]nonane
3-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-6-nitrodibenzo[b,d]thiophene 5,5-dioxide
Qualität
Research Chemical
Eigenschaften
Molare Masse 385.44
CAS RN [1456877-71-6]
Reinheit ≥ 95 %
- Reddish solid
- slightly soluble in dimethyl sulfoxide
Zertifikate
CoA: appearance, ¹H NMR spectrum (identity), HPLC (purity)
Literatur
Gao Y. et al. Derivatives of dibenzothiophene for positron emission tomography imaging of α7-nicotinic acetylcholine receptors. J. Med. Chem. 2013, 56, 7574–7589.
Horti A.G. et al. ¹⁸F-ASEM, a Radiolabeled Antagonist for Imaging the α7-Nicotinic Acetylcholine Receptor with PET. J. Nucl. Med. 2014, 55, 672–677.
Wong D.F. et al. Human Brain Imaging of α7 nAChR with [¹⁸F]ASEM: a New PET Radiotracer for Neuropsychiatry and Determination of Drug Occupancy. Mol. Imaging Biol. 2014, 16, 730–738.
Horti A.G. Development of [¹⁸F]ASEM, a specific radiotracer for quantification of the α7-nAChR with positron-emission tomography. Biochem. Pharmacol. 2015, 97, 566–575.
Ravert H.T. et al. Microwave-assisted radiosynthesis of [¹⁸F]ASEM, a radiolabeled α7-nicotinic acetylcholine receptor antagonist. J. Labelled Compd. Radiopharm. 2015, 58, 180–182.
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| Produkt | Produktnummer | Füllmenge | Anzahl | ||
|---|---|---|---|---|---|
| /de/Produkte/Kleine-Molekuele-und-Peptide/chemical/4f8d9035-b47c-474b-809e-c7c475296376 | Precursor | Produktnummer: 3371 | Füllmenge: 10 mg | ||
| /de/Produkte/Kleine-Molekuele-und-Peptide/chemical/4f8d9035-b47c-474b-809e-c7c475296376 | Precursor | Produktnummer: 3371 |
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