Kleine Moleküle & Peptide

PSMA I&T acetate (GMP)

Precursor for radiometal-labelled PSMA I&T (PSMA: prostate-specific membrane antigen)

(R)-DOTAGA-(I-y)fk(Sub-KuE)

Sequence: (R)-DOTAGA-D-Tyr(3-I)-D-Phe-D-Lys[Sub-Glu-CO-Lys] acetate

Qualität

GMP Product

Eigenschaften

Molare Masse 1498.37 (PSMA I&T)

CAS RN [2192281-54-0] (PSMA I&T)

  • White to off-white solid
  • Tested for bioburden and bacterial endotoxins.

Literatur

Baum R.P. et al. ¹⁷⁷Lu-Labeled Prostate-Specific Membrane Antigen Radioligand Therapy of Metastatic Castration-Resistant Prostate Cancer: Safety and Efficacy. J. Nucl. Med. 2016, 57, 1006–1013.

Eiber M. et al. Systemic Radioligand Therapy with ¹⁷⁷Lu Labeled Prostate Specific Membrane Antigen Ligand for Imaging and Therapy in Patients with Metastatic Castration Resistant Prostate Cancer. J. Nucl. Med., 2016, 57(supplement 2): p. 61–61.

Schottelius M. et al. [¹¹¹In] PSMA-I&T: expanding the spectrum of PSMA-I&T applications towards SPECT and radioguided surgery. EJNMMI Res. 2015, 5, 68.

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ProduktnummerFüllmengeAnzahl
Produktnummer: 99383

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