Kleine Moleküle & Peptide

ABX474

Precursor for [99mTc]TcO-ABX474

ABX474

Sequence: Glu-CO-Lys-[(Sub)-DLys-Glu-Glu-BAT] (BAT: 5-((2-mercapto-2-methylpropyl)(2-((2-mercapto-2-methylpropyl)amino)ethyl)amino)pentanoic acid; Sub: suberic acid)

Qualität

Research Chemical

Eigenschaften

Molare Masse 1180.44 (net peptide)

CAS RN [not yet assigned]

Reinheit ≥ 95 %

  • White to off-white solid
  • soluble in water, methanol, dimethyl sulfoxide

Zertifikate

CoA: ESI-MS (identity), HPLC (purity)

Literatur

Lis et al. Development of [99mTc]TcO-ABX474: Design, Synthesis, and Biological Evaluation of PSMA-Binding Technetium-99m Radioligands for SPECT Imaging of Prostate Cancer. Journal of Medicinal Chemistry 2025, https://doi.org/10.1021/acs.jmedchem.4c02767

Rahbar et al. First Experiences with the new 99mTc labelled PSMA ligand [99mTc]TcO-ABX474 in Patients with Advanced Prostate Cancer Prior to PSMA targeted Radioligand Therapy. Journal of Nuclear Medicine June 2024, 65 (supplement 2), 241711.

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ProduktnummerFüllmengeAnzahl
Produktnummer: 99470
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