Kleine Moleküle & Peptide

Desmethyl-MK-8278 (GMP)

Precursor for [¹¹C]MK-8278

trans-5'-Hydroxy-3'-oxo-N-methyl-N-(2-piperidin-1-ylethyl)-spiro[cyclohexane-1,1'-(3'H)-isobenzofuran]-4-carboxamide; [¹¹C]MK-8278 precursor

Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]-4-carboxamide, 5'-hydroxy-N-methyl-3'-oxo-N-[2-(1-piperidinyl)ethyl]-, (1α,4β)-

Qualität

GMP Product

Eigenschaften

Molare Masse 386.48

CAS RN [879368-41-9]

Reinheit ≥ 97 %

  • Colorless to off-white foam/solid

Zertifikate

CoA: appearance, ¹H NMR spectrum, HPLC

Literatur

Van Laere K. J. et al. ¹¹C-MK-8278 PET as a Tool for Pharmacodynamic Brain Occupancy of Histamine 3 Receptor Inverse Agonists. J. Nucl. Med. 2014, 55, 65–72.

Hamill T. G. et al. Inverse Agonist Histamine H3 Receptor PET Tracers Labelled With Carbon-11 or Fluorine-18. Synapse 2009, 63, 1122–1132.

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ProduktnummerFüllmengeAnzahl
Produktnummer: 3721

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