5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine
Precursor 2 for [¹⁸F]FMAU (2'-deoxy-2'-[¹⁸F]fluoro-5-methyl-1-β-D-arabinofuranosyluracil)
2,4-Bis(trimethylsiloxy)-5-methylpyrimidine; 2,4-Bis(trimethylsilyl)-5-methyluracil; 2,4-Bis-O-(trimethylsilyl)thymine; O,O'-Bis(trimethylsilyl)thymine; Bis(O-trimethylsilyl)thymine
CA index name: Pyrimidine, 5-methyl-2,4-bis[(trimethylsilyl)oxy]-
Qualität
Research Chemical
Eigenschaften
Molare Masse 270.48
CAS RN [7288-28-0]
Reinheit ≥ 95 %
- Colorless solid or liquid
Zertifikate
CoA: appearance, ¹H and ¹³C NMR spectra
Literatur
Mangner T.J. et al. Synthesis of 2'-deoxy-2'-[¹⁸F]fluoro-β-D-arabinofuranosyl nucleosides, [¹⁸F]FAU, [¹⁸F]FMAU, [¹⁸F]FBAU, [¹⁸F]FIAU, as potential PET agents for imaging cellular proliferation. Nucl. Med. Biol. 2003, 30, 215–224.
Buursma A.R. et al. ¹⁸F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: in-vitro comparison with other PET tracers. Nucl. Med. Commun. 2006, 27, 25–30.
Alauddin M.M. et al. Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model. Mol. Imaging 2004, 3, 76–84.
Alauddin M.M. et al. Synthesis and evaluation of 2'-deoxy-2'-¹⁸F-fluoro-5-fluoro-1-β-D-arabinofuranosyluracil as a potential PET imaging agent for suicide gene expression. J. Nucl. Med. 2004, 45, 2063–2069
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Produkt | Produktnummer | Füllmenge | Anzahl | ||
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/de/Produkte/Kleine-Molekuele-und-Peptide/chemical/7bea4590-8267-449a-8b14-8e2934930971 | Precursor | Produktnummer: 2872 | Füllmenge: 100 mg | ||
/de/Produkte/Kleine-Molekuele-und-Peptide/chemical/7bea4590-8267-449a-8b14-8e2934930971 | Precursor | Produktnummer: 2872 |