Kleine Moleküle & Peptide

THK-5351 precursor

THK-5352; THK-5152S

(2S)-3-((2-(6-(methylamino)pyridin-3-yl)quinolin-6-yl)oxy)-2-((tetrahydro-2H-pyran-2-yl)oxy)propyl 4-methylbenzenesulfonate

Qualität

Research Chemical

Eigenschaften

Molare Masse 563.67

CAS RN [1707147-35-0]

Reinheit ≥ 95 %

  • white to off-white solid
  • soluble in chloroform, acetonitrile, dimethyl sulfoxide

Zertifikate

CoA: appearance, 1H NMR spectrum (identity), HPLC (purity)

Literatur

Betthauser, T.J. et al. Characterization of the radiosynthesis and purification of [18F]THK-5351, a PET ligand for neurofibrillary tau. Appl. Radiat. Isot. 2017, 130, 230–237.

Harada, R. et al. 18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease. J. Nucl. Med. 2016, 57, 208−214.

Harada, R. et al. Correlations of 18F-THK5351 PET with Postmortem Burden of Tau and Astrogliosis in Alzheimer Disease. J. Nucl. Med. 2018, 59, 671−674.

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ProduktnummerFüllmengeAnzahl
Produktnummer: 5198
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