Kleine Moleküle & Peptide
MK-9470 reference standard
Reference standard for [¹⁸F]MK-9470
Propanamide, N-[(1S,2S)-2-(3-cyanophenyl)-3-[4-(2-fluoroethoxy)phenyl]-1-methylpropyl]-2-methyl-2-[(5-methyl-2-pyridinyl)oxy]-; N-{(1S,2S)-2-(3-Cyanophenyl)-3-[4-(2-fluoroethoxy)phenyl)]-1-methylpropyl}-2-methyl-2-[(5-methylpyridin-2-yl)oxy]propanamide; [¹⁸F]MK-9470 standard
N-((2S,3S)-3-(3-cyanophenyl)-4-(4-(2-fluoroethoxy)phenyl)butan-2-yl)-2-methyl-2-(5-methylpyridin-2-yloxy)propanamide
Qualität
Research Chemical
Eigenschaften
Molare Masse 489.58
CAS RN [947371-30-4]
Reinheit ≥ 95 %
- Colorless to off-white solid
- soluble in dimethyl sulfoxide, chloroform, methanol, ethyl acetate
Zertifikate
CoA: appearance, ¹H and ¹⁹F-NMR spectra (identity), HPLC (purity)
Literatur
Thomae D. et al. Automated one-step radiosynthesis of the CB1 receptor imaging agent [¹⁸F]MK-9470. J. Labelled Compd. Radiopharm. 2014, 57, 611–614.
Liu P. et al. Discovery of N-{(1S,2S)-2-(3-cyanophenyl)- 3-[4-(2-[¹⁸F]fluoroethoxy)phenyl]-1-methylpropyl}- 2-methyl-2-[(5-methylpyridin- 2-yl)oxy]propanamide, a cannabinoid-1 receptor positron emission tomography tracer suitable for clinical use. J. Med. Chem. 2007, 50, 3427–3430.
Burns H.D. et al. [¹⁸F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor. PNAS 2007, 104, 9800–9805.
Emonds K.M. et al. ¹⁸F-MK-9470 PET imaging of the type 1 cannabinoid receptor in prostate carcinoma: a pilot study. EJNMMI Research 2013, 3, 59.
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| Produkt | Produktnummer | Füllmenge | Anzahl | ||
|---|---|---|---|---|---|
| /de/Produkte/Kleine-Molekuele-und-Peptide/chemical/bc89a39f-7caa-4bb0-ab35-10399553d513 | Reference Standard | Produktnummer: 5652 |
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