Kleine Moleküle & Peptide

Sifalin-TATE precursor (Acetate salt)

Precursor for [¹⁸F]Sifalin TATE

Sequence: SiFAlin-Aoa-Asn(AcNH-ß-Glc)-Asp-Asp-O2Oc-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr-OH, cyclic disulfide (SiFAlin: N-(4-(di-tert-butylfluorosilyl)benzyl)-N,N-dimethyl-4-oxobutan-1-ammonium acetate; Aoa: aminooxyacetic acid; Asn(AcNH-ß-Glc): N-β-[2-(acetylamino)-deoxy-2-β-glucopyranosyl]-L-asparagine; O2Oc: 8-amino-3,6-dioxaoctanoic acid)

Qualität

Research Chemical

Eigenschaften

Molare Masse 2163.5 (net peptide)

CAS RN [not yet assigned]

Reinheit ≥ 95 %

  • White to off-white solid
  • soluble in water

Zertifikate

CoA: HPLC (purity), HPLC-MS (identity)

Literatur

Litau S. et al. Next Generation of SiFAlin-Based TATE Derivatives for PET Imaging of SSTR-Positive Tumors: Influence of Molecular Design on In Vitro SSTR Binding and In Vivo Pharmacokinetics. Bioconjug. Chem. 2015, 26, 2350–2359.

Niedermoser S. et al. In Vivo Evaluation of ¹⁸F-SiFAlin-Modified TATE: A Potential Challenge for ⁶⁸Ga-DOTATATE, the Clinical Gold Standard for Somatostatin Receptor Imaging with PET. J. Nucl. Med. 2015, 56, 1100–5.

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ProduktnummerFüllmengeAnzahl
Produktnummer: 97521
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