Qualität

Eigenschaften

Molare Masse 530.40

CAS RN [126766-43-6]

Reinheit ≥ 95 %

• colorless to off-white solid
• soluble in dimethyl sulfoxide, ethanol, methanol, acetone

Zertifikate

CoA: appearance, ¹H and ¹³C NMR spectra

Literatur

Ravert H.T. et al. [¹¹C]-GR 89696, a potent kappa opiate receptor radioligand, in vivo binding of the R and S enantiomers. Nuc. Med. Biol. 2002, 29, 47–53.

Talbot P.S. et al. ¹¹C-GR 103545, a Radiotracer for Imaging κ-Opioid Receptors In Vivo with PET: Synthesis and Evaluation in Baboons. J. Nucl. Med. 2005, 46, 484–494.

Naylor A. et al. A Potent New class of κ-Receptor Agonist: 4-Substituted 1-(Arylacetyl)-2-[(dialkylamino)methyl]piperazines. J. Med. Chem. 1993, 36, 2075–2083.

Schoultz B.W. et al. A New Method for Radiosynthesis of ¹¹C-Labeled Carbamate Groups and its Application for a Highly Efficient Synthesis of the Kappa-Opioid Receptor Tracer [¹¹C]GR 103545. The Open Med. Chem. J. 2008, 2 ,72–74.