Kleine Moleküle & Peptide
DOTA-TOC (GMP)
Precursor for radiolabelled DOTA-TOC
DOTA-TOC acetate; DOTA-[Tyr3]-octreotide; Edotreotide; CA index name: L-Cysteinamide, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic(2→7)-disulfide, supplied as acetate salt
Sequence: DOTA-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr(ol), cyclic disulfide
Qualität
GMP Product
Eigenschaften
Molare Masse 1421.7 (net peptide)
CAS RN [204318-14-9]
Reinheit ≥ 98 %
- White to off-white powder
Zertifikate
CoA: appearance, HPLC (identity, purity, assay), GC (residual Solvents, water content, counter-ion), microbiology test
Literatur
Forrer F. et al. Targeted radionuclide therapy with 90Y-DOTATOC in patients with neuroendocrine tumors. Anticancer Res. 2006, 26, 703–707.
Koukouraki S. et al. Evaluation of the pharmacokinetics of (68)Ga-DOTATOC in patients with metastatic neuroendocrine tumours scheduled for (90)Y-DOTATOC therapy. Eur. J. Nucl. Med. Mol. Imaging 2006, 33, 460–466.
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| Produkt | Produktnummer | Füllmenge | Anzahl | ||
|---|---|---|---|---|---|
| /de/Produkte/Kleine-Molekuele-und-Peptide/chemical/47fb128b-947b-4b80-98f0-a10d2344810f | Chemicals | Produktnummer: 9702 |
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