Kleine Moleküle & Peptide

Lu-DOTA-TOC

Referenzstandard für [¹⁷⁷Lu]Lu-DOTA-TOC

Lu-Edotreotide; Lu-SMT487; Lu-DOTA-[Tyr3]octreotide; Lutetium-175Lu, [N-[2-[4,7,10-tris[(carboxy-κO)methyl]-1,4,7,10-tetraazacyclododec-1-yl]acetyl-κO]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic(2→7)-disulfidato(3-)]-; Lutetium-175Lu, [N-[[4,7,10-tris[(carboxy-κO)methyl]-1,4,7,10-tetraazacyclododec-1-yl]acetyl-κO]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic(2→7)-disulfidato(3-)]-

Sequence: DOTA(Lu)-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr(ol), cyclic disulfide.

Qualität

Research Chemical

Eigenschaften

Molare Masse 1593.58 (Lu-DOTA-TOC)

CAS RN [321835-55-6] ([¹⁷⁷Lu]-DOTA-TOC)

Reinheit ≥ 95 %

  • Colorless to off-white solid

Zertifikate

CoA: appearance, MS (identity), HPLC (purity)

Literatur

Villard L. et al. Cohort study of somatostatin-based radiopeptide therapy with [⁹⁰Y-DOTA]-TOC versus [⁹⁰Y-DOTA]-TOC plus [¹⁷⁷Lu-DOTA]-TOC in neuroendocrine cancers. J. Clin. Oncol. 2012, 30, 1100–1106.

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Produktnummer: 9705

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