Kleine Moleküle & Peptide
[¹⁸F]PBR06 precursor (GMP)
Precursor for [¹⁸F]PBR06
Toluene-4-sulfonic acid [(2,5-dimethoxy-benzyl)-(2-phenoxy-phenyl)-carbamoyl]-methyl ester; Acetamide, N-[(2,5-dimethoxyphenyl)methyl]-2-[[(4-methylphenyl)sulfonyl]oxy]-N-(2-phenoxyphenyl)-; [¹⁸F]PBR06 precursor
2-((2,5-Dimethoxybenzyl)(2-phenoxyphenyl)amino)-2-oxoethyl 4-methylbenzenesulfonate
Qualität
GMP Product
Eigenschaften
Molare Masse 547.62
CAS RN [1334484-14-8]
Reinheit ≥ 97 %
- colorless to yellowish solid
- soluble in dimethyl sulfoxide, chloroform, ethyl acetate
Literatur
Imaizumi M. et al. Kinetic evaluation in nonhuman primates of two new PET ligands for peripheral benzodiazepine receptors in brain. Synapse 2007, 61, 595–605.
Briard E. et al. Single-Step High-Yield Radiosynthesis and Evaluation of a Sensitive ¹⁸F-Labeled Ligand for Imaging Brain Peripheral Benzodiazepine Receptors with PET. J. Med. Chem. 2009, 52, 688–699.
Wang M. et al. Synthesis of [¹¹C]PBR06 and [¹⁸F]PBR06 as agents for positron emission tomographic (PET) imaging of the translocator protein (TSPO). Steroids 2011, 76, 1331–1340.
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| Produkt | Produktnummer | Füllmenge | Anzahl | ||
|---|---|---|---|---|---|
| /de/Produkte/Kleine-Molekuele-und-Peptide/chemical/5839099a-14e4-4d2e-a17e-bae3283fb199 | Precursor | Produktnummer: 1671 |
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